Polysaccharides as building blocks for nanotherapeutics

Mizrahy S and  Peer D Chem Soc Rev. (2012), 41(7):2623-2640. The use of polysaccharides as building blocks in the development of nano-sized drug delivery systems is rapidly growing. This can be attributed to the outstanding virtues of polysaccharides such as biocompatibility, biodegradability, low toxicity and low cost. In addition, the variety of physicochemical properties and the ease of chemical modifications enable […]

Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles

Srinivas Ramishetti*, Ranit Kedmi*, Meir Goldsmith, Fransisca Leonard, Andrew G. Sprague, Biana Godin, Michael Gozin, Pieter R. Cullis, Derek M. Dykxhoorn, and Dan Peer

A modular platform for targeted RNAi therapeutics

Ranit Kedmi*, Nuphar Veiga*, Srinivas Ramishetti, Meir Goldsmith, Daniel Rosenblum,
Niels Dammes, Inbal Hazan-Halevy, Limor Nahary, Shani Leviatan-Ben-Arye, Michael Harlev,
Mark Behlke, Itai Benhar, Judy Lieberman and Dan Peer

Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes

Nuphar Veiga, Meir Goldsmith, Yasmin Granot, Daniel Rosenblum, Niels Dammes, Ranit Kedmi, Srinivas Ramishetti & Dan Peer