This research aims to develop novel nucleic acids-based therapeutics for hematological malignancies
The focus of this research is to design novel neurotrophic virus inspired nanotherapeutics to deliver nucleic acids into the CNS. We aim to utilize such therapeutic modality and develop new remedies for neurodevelopmental disorders.
We aspire to utilize oligonucleotides loaded LNPs for in vivo reprograming of leukocytes and thus to design novel immunomodulatory therapeutic approaches for autoimmune disorders and cancer.
The goal of this project is to explore resistance pathways of cancer cells and translate the acquired knowledge by designing novel RNAi-based nanotherapeutics.
We aim to utilize RNA-loaded lipid nanoparticles in order to design new therapeutic modalities for various malignancies, including head & neck cancer, glioblastoma and breast cancer.
We aim to design novel platforms for a selective delivery of therapeutic payload to specific target cells, thus increasing the efficiency and reducing adverse effects.
This research aims to broaden the nanotechnology toolbox by designing new, highly efficient, methodologies for nucleic acids delivery.