Dual–Targeted Lipid Nano-therapeutic Boost for Chemo–Immunotherapy of Cancer
Researchers from Tel Aviv University proved that a drug delivery system based on lipid nanoparticles can utilize RNA to overcome resistance to both chemotherapy and immunotherapy in cancer treatments. The study opens a new path to a personalized and precisely targeted battle against cancer. The results were published in the scientific journal Advanced Materials. The […]
Israeli Scientists Kill Cancer With Revolutionary DNA-Altering Treatment
Tel Aviv University researchers use tiny ‘molecular scissors’ to target aggressive metastatic cancer cells. Israeli scientists have developed a cutting-edge nanotechnology system that can destroy cancerous cells in mice. The Tel Aviv University team of researchers pioneered a treatment method that is so precise, it is almost as if tiny molecular scissors were being used […]
TAU Develops Targeted Delivery of Therapeutic RNAs to Cancer Cells Only
Prof. Peer says , “We were able to organize the delivery system in such a way that we target to only 14.9% of the cells that were involved in the inflammatory condition of the disease, without adversely affecting the other, non-involved, cells, which are completely healthy. Through specific binding to the cell sub-population, while delivering […]
A Matter of Time- mRNA Technology, Lipid Nanoparticles and Bioinformatics have turned the pharmaceutical industry upside-down
“without lipid nanoparticles, there is no mRNA vaccine, no 95% efficacy, and the route out of the pandemics is many times longer and narrower”. Tim Guns speaks to Robert langer, MIT institute, and Moderna cofounder, Pieter Cullis, head of the Nanomedicine Research group at the University of British Columbia and co-founder of Acutias, and Dan […]
Team Award Winners: Infinite Possibilities Teams Awards
The 2021 MolecularCloud Distinguished Research Awards for outstanding research achievements in the genome-editing field. Team Award Winners – The Peer Dan Team- Infinite Possibilities Teams The lab is highly dynamic, multidisciplinary, and focuses on developing targeted vehicles for cell-specific delivery of novel molecular medicines using RNAi, mRNA, saRNA, DNA, and novel genome editing strategies. Our goal […]
Handbook of Harnessing Biomaterials in Nanomedicine Edited By Dan Peer
See our new edition of the handbook Harnessing Biomaterials in Nanomedicine, edited by Prof. Dan Peer. https://www.taylorfrancis.com/books/handbook-harnessing-biomaterials-nanomedicine-dan-peer/e/10.1201/9781003125259
Design of mRNA vaccines delivered via novel lipid nanoparticles
Elia U, Ramishetti S, Rosenfeld R, Dammes N, Bar-Haim E, Somu Naidu G, Makdasi E, Yahalom-Ronen Y, Tamir H, Paran N, Cohen O, Peer D
CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy
Ranit Kedmi*, Nuphar Veiga*, Srinivas Ramishetti, Meir Goldsmith, Daniel Rosenblum,
Niels Dammes, Inbal Hazan-Halevy, Limor Nahary, Shani Leviatan-Ben-Arye, Michael Harlev,
Mark Behlke, Itai Benhar, Judy Lieberman and Dan Peer
Progress and challenges towards targeted delivery of cancer therapeutics
Rosenblum D, Joshi N, Tao W, Karp JM and Peer D Nat Commun (2018) 9;1410, 1-12 Targeted delivery approaches for cancer therapeutics have shown a steep rise over the past few decades. However, compared to the plethora of successful pre-clinical studies, only 15 passively targeted nanocarriers (NCs) have been approved for clinical use and none […]
Special delivery: targeted therapy with small RNAs
Peer D, Lieberman J Gene Ther (2011) 18(12):1127-1133. Harnessing RNA interference using small RNA-based drugs has great potential to develop drugs designed to knock down expression of any disease-causing gene, thereby greatly expanding the universe of possible drug targets. However, delivering small RNAs into specific tissues and cells is still a hurdle. Here, we review recent […]